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A fast method for inferring phylogenetic networks displaying phylogenetic trees

发布时间:2024-05-31 作者:77779193永利集团 浏览次数:
Speaker: 张洛欣 DateTime: 2024年6月13日(周四)上午10:00-11:00
Brief Introduction to Speaker:

Phylogenetic networks are rooted, acyclic directed graph in which leaves are labelled with genes, genomes or species. They are used to model evolution with reticulate events. The reconstruction of phylogenetic networks is an important but challenging problem in phylogenetics and genome evolution, as the space of phylogenetic networks is vast and cannot be sampled well. One approach to the problem is to solve the minimum phylogenetic network problem, in which phylogenetic trees are first inferred, then the smallest phylogenetic network that displays all the trees is computed. A tree-child network is a phylogenetic network satisfying the condition that every non-leaf node has at least one child that is of indegree one.  As an application of a vector representation of trees which we introduced recently, we develop a new method that infers the minimum tree-child network by aligning lineage taxon strings in the phylogenetic trees, where we reduce the tree-child network inference problem to the shortest common super-sequence problem. This algorithmic innovation enables us to get around the limitations of the existing programs for phylogenetic network inference.

Place: M323
Abstract:张洛欣教授在加拿大滑铁卢大学获计算机博士学位,现为新加坡国立大学数学系教授、博士生导师。主要研究方向为计算生物学、离散应用数学和理论计算机科学,在生物序列进化分析理论和算法方面发表上百篇论文,2005年获国家自然科学基金委B类杰出青年基金,1997年获新加坡李光耀博士后研究奖。